Incidence and predictive factors of Balkan Endemic Nephropathy: A longitudinal study
نویسندگان
چکیده
منابع مشابه
Endemic (Balkan) nephropathy is aristolochic acid nephropathy.
Endemic nephropathy is a syndrome that comprises two entities: chronic interstitial nephropathy and urothelial cell cancers predominantly of the upper urinary tract. The etiological agent for the disease is aristolochic acid, a compound found in the plants of Aristolochia spp. The development of urothelial cancers is characterized by the formation of aristolactam DNA adducts leading to mutation...
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The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
متن کاملEarly Screening of Balkan Endemic Nephropathy
Introduction Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical implementing of in-field screening of B...
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RENAL INTERSTITIAL FIBROSIS IS A MAJOR FEATURE OF BALKAN ENDEMIC NEPHROPATHY (BEN) G. A. Müller, M. Zeisberg, F Strutz Dept. of Nephrology & Rheumatology, Georg-August Universität Göttingen, 37075 Göttingen, Germany Balkan Nephropathy is a common renal disease in the Balkan region which often leads to endstage renal failure. The pathogenesis of this disease is still unknown, however, the pathwa...
متن کاملGenetic, Genomic and Epigenomic Studies of Balkan Endemic Nephropathy (Ben).
BEN is a primary, chronic tubulointerstitial nephritis characterized with chronic anemia, absence of edema, xantoderma, normal blood pressure and normal findings on the fundus oculi. The disease is distributed in restricted areas in Bulgaria, Romania, Croatia, Bosnia, Former Yugoslavia. Despite numerous studies on genetic and environmental factors and their possible involvement in BEN, its etio...
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ژورنال
عنوان ژورنال: Saudi Journal of Kidney Diseases and Transplantation
سال: 2014
ISSN: 1319-2442
DOI: 10.4103/1319-2442.128539